Project
What would it take to make a virtual microbiology lab?
Computational Biology offers a valuable complement to complex experimental approaches to study infectious diseases like HIV and tuberculosis.
Project
Integration of structure/function predictions into the CERI emerging threat genomic surveillance pipeline
The Centre for Epidemiology Research and Innovation collects high-precision and timely data on emerging health threats by carrying out a world-class genomic surveillance effort.
Publication
Rapid evolutionary change in trait correlations of single proteins
Dasmeh, P., Zheng, J., Erdoğan, A. N., Tokuriki, N., & Wagner, A. (2024). Rapid evolutionary change in trait correlations of single prot...
Publication
The role of theorem proving in systems biology
Wolkenhauer, Olaf; Shibata, Darryl; Mesarovic, Mihajlo D. 2012. The role of theorem proving in systems biology. JOURNAL OF THEORETICAL BIOLO...
Publication
The road from systems biology to systems medicine
Olaf Wolkenhauer, Charles Auffray, Robert Jaster, et al. 2013. The road from systems biology to systems medicine. Pedeatric Research, 73 (4)...
Publication
Why model?
Olaf Wolkenhauer. 2014. Why model? Froniers in Physiology, 5 (21), 1-14. doi:10.3389/fphys.2014.00021
Publication
Enabling multiscale modeling in systems medicine
Olaf Wolkenhauer, Charles Auffray, Olivier Brass, et al. 2014. Enabling multiscale modeling in systems medicine. Genome Medicine, 6 (3) Arti...
Publication
Cooperative gene regulation by microRNA pairs and their identification using a computational workflow
Ulf Schmitz, Ulf, Xin Lai, Felix Winter, Olaf Wolkenhauer et al. 2014. Cooperative gene regulation by microRNA pairs and their identificatio...
Publication
Hybrid modeling of the crosstalk between signaling and transcriptional networks using ordinary differential equations and multi-valued logic
Faiz M. Khan, Ulf Schmitz, Svetoslav Nikolov, David Putzer, Brigitte M. Puetzer, Olaf Wolkenhauer and Julio Vera. 2014. Hybrid modeling of t...
Publication
Anti-Inflammatory Effects of Reactive Oxygen Species – a Multi-Valued Logical Model Validated by Formal Concept Analysis
Wollbold, Johannes, Robert Jaster, Sarah Müller, Katja Rateitschak, and Olaf Wolkenhauer. 2014. Anti-Inflammatory Effects of Reactive Oxygen...
Publication
Influence of Antifreeze Proteins on the Ice/Water Interface
Todde, Guido, Sven Hovmöller, and Aatto Laaksonen. 2015. Influence of Antifreeze Proteins on the Ice/Water Interface. The Journal of Physica...
Publication
An Explicit Numerical Scheme to Efficiently Simulate Molecular Diffusion in Environments with Dynamically Changing Barriers
Kossow, Christina, Stefan Rybacki, Thomas Millat, Katja Rateitschak, Robert Jaster, Adelinde M. Uhrmacher, and Olaf Wolkenhauer. 2015. An Ex...
Publication
Annotation-Based Feature Extraction from Sets of SBML Models
Alm, Rebekka, Dagmar Waltemath, Markus Wolfien, Olaf Wolkenhauer, and Ron Henkel. 2015. Annotation-Based Feature Extraction from Sets of SBM...
Publication
Naïve Bayes Classifier Predicts Functional microRNA Target Interactions in Colorectal Cancer
Amirkhah, Raheleh, Ali Farazmand, Shailendra K. Gupta, Hamed Ahmadi, Olaf Wolkenhauer, and Ulf Schmitz. 2015. Naïve Bayes Classifier Predict...
Publication
TRAPLINE: A Standardized and Automated Pipeline for RNA Sequencing Data Analysis, Evaluation and Annotation
Wolfien, Markus, Christian Rimmbach, Ulf Schmitz, Julia Jeannine Jung, Stefan Krebs, Gustav Steinhoff, Robert David, and Olaf Wolkenhauer. 2...
Publication
COMODI: An Ontology to Characterise Differences in Versions of Computational Models in Biology
Scharm, Martin, Dagmar Waltemath, Pedro Mendes, and Olaf Wolkenhauer. 2016. COMODI: An Ontology to Characterise Differences in Versions of C...
Publication
An Algorithm to Detect and Communicate the Differences in Computational Models Describing Biological Systems
Scharm, Martin, Olaf Wolkenhauer, and Dagmar Waltemath. 2016. An Algorithm to Detect and Communicate the Differences in Computational Models...
Publication
Understanding microRNA-Mediated Gene Regulatory Networks through Mathematical Modelling
Lai, Xin, Olaf Wolkenhauer, and Julio Vera. 2016. Understanding microRNA-Mediated Gene Regulatory Networks through Mathematical Modelling. N...
Publication
Personalized Cancer Immunotherapy Using Systems Medicine Approaches
Gupta, Shailendra K, Tanushree Jaitly, Ulf Schmitz, Gerold Schuler, Olaf Wolkenhauer, and Julio Vera. 2016. Personalized Cancer Immunotherap...
Publication
Systems Medicine
Schmitz, Ulf and Olaf Wolkenhauer. 2016. Systems Medicine. edited by Ulf Schmitz and Olaf Wolkenhauer. New York, NY: Springer New York. http...
Publication
Network-Assisted Disease Classification and Biomarker Discovery
Strunz, Sonja, Olaf Wolkenhauer, and Alberto de la Fuente. 2016. Network-Assisted Disease Classification and Biomarker Discovery. Pp. 353–74...