The Stellenbosch Institute for Advanced Study

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Ideas

Topic: Structural Biology

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Project

Breaking the ice: how integrating cryogenic Electron Microscopy can overcome historical scientific isolation and enable local pharmaceutical and vaccine Development in South Africa.

With the award of the 2017 Nobel Prize in Chemistry to three pioneers in cryogenic electron microscopy, the world was awakened to the cutting-edge technology of 'cryo-EM'.

Lydia-Marie Joubert Lydia-Marie Joubert

Publication

Structural basis of streptomycin off-target binding to human mitoribosome

Yuzuru Itoh, Aas Khawaja, Vivek Sight, Andreas Naschberger, Joanna Rorbach, Alexey Amunts. 2023. Structural basis of streptomycin off-target...

Joanna Rorbach Joanna Rorbach

Project

Alternative targets for Antibiotics, fighting infection with higher specificity

Antibiotic resistant is a global problem that will only increase over time and is further highly relevant for the tuberculosis patients of South Africa.

Katja Petzold Katja Petzold

Publication

Combining MD Simulations and NMR Spectroscopy for Molecular Insight and Methodological Synergy: The Integrated MD-NMR Method

Mocci, Francesca, and Aatto Laaksonen. 2015. Combining MD Simulations and NMR Spectroscopy for Molecular Insight and Methodological Synergy:...

Aatto Laaksonen Aatto Laaksonen

Project

Complexity and emergent properties in the spider’s webs and silks

Spider webs are superb examples of functional structures that emerge as the animal builds her web.

Fritz Vollrath Fritz Vollrath
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