Project
Understanding Alzheimer’s Disease: Basic mechanisms and clinical developments
The abnormal processing of amyloid precursor protein (APP), aggregation of Aβ, Tau hyper phosphorylation and propagation of these abnormally folded proteins have been collectively recognized as hallmarks of the initial, biochemical phase of Alzheimer’s Disease (AD) [De Strooper 2016].
Publication
Death Domain Signaling by Disulfide-Linked Dimers of the p75 Neurotrophin Receptor Mediates Neuronal Death in the CNS
Tanaka, K, CE Kelly, KY Goh, KB Lim, and Carlos F Ibanez. 2016. Death Domain Signaling by Disulfide-Linked Dimers of the p75 Neurotrophin Re...