Project
Alternative targets for Antibiotics, fighting infection with higher specificity
Antibiotic resistant is a global problem that will only increase over time and is further highly relevant for the tuberculosis patients of South Africa.
Publication
Mce3R Stress-Resistance Pathway Is Vulnerable to Small-Molecule Targeting That Improves Tuberculosis Drug Activities
Yang, Xinxin, Tianao Yuan, Rui Ma, Kieran I Chacko, Melissa Smith, Gintaras Deikus, Robert Sebra, Andrew Kasarskis, Harm van Brakel, Scott G...
Publication
Catabolism of the Cholesterol Side Chain in Mycobacterium tuberculosis is Controlled by a Redox-Sensitive Thiol Switch
Lu, Rui, Christin Schaefer, Natasha M Nesbitt, Jochen Kuper, Caroline Kisker, & Nicole S Sampson. 2017. Catabolism of the Cholesterol Side C...