Project
Information and Codes in Biochemistry
Biochemists traditionally accept the view that life is an extremely complex form of chemistry (the Chemical paradigm), a view which implies that genetic information and the genetic code are but metaphorical concepts because they cannot be described by physical quantities.
Project
Generation of a Chronic Myeloid Leukemia single-cell genomic atlas
Chronic Myeloid Leukemia (CML) is an aggressive type of blood cancer that requires life-long therapy.
Publication
Synthetic deformylated α-helical PSMα3 as a selective inhibitor of human amyloid aggregation
Recommended Citation Kalitnik, A., Wojciechowska, A. W., Wojciechowski, J. W., Polańska, O., Sareło, P., Szefczyk, M., & Kotulska, M. (2...
Project
Developing molecular tools to study genetics codes using single-cell genomics
The ability to characterize cell types and their genetic programs across tissues, have profoundly accelerated through the development of single-cell sequencing methods.
Publication
Human mitochondria require mtRF1 for translation termination at non-canonical stop codons
Krüger, Annika, Cristina Remes, Dmitrii Igorevich Shiriaev, Yong Liu, Henrik Spåhr, Rolf Wibom, Ilian Atanassov, Minh Duc Nguyen, Barry S. C...
Publication
Translation initiation of leaderless and polycistronic transcripts in mammalian mitochondria
Remes, Cristina Remes, Anas Khawaja, Sarah F. Pearce, Adam M. Dinan, Shreekara Gopalakrishna, Miriam Cipullo, Vasileios Kyriakidis, Jingdian...
Publication
Activin receptor ALK4 promotes adipose tissue hyperplasia by suppressing differentiation of adipocyte precursors
Lee, Ee-Soo, Tingqing Guo, Raj Kamal Srivastava, Assim Shabbir and Carlos F. Ibáñez. 2023. Activin receptor ALK4 promotes adipose tissue hyp...
Publication
Multiple Novel Traits without Immediate Benefits Originate in Bacteria Evolving on Single Antibiotics
Karve, Shraddha and Andreas Wagner. 2022. Multiple Novel Traits without Immediate Benefits Originate in Bacteria Evolving on Single Antibiot...
Publication
The length scale of multivalent interactions is evolutionarily conserved in fungal and vertebrate phase-separating proteins
Dasmeh, Pouria, Roman Doronin and Andreas Wagner. 2022. The length scale of multivalent interactions is evolutionarily conserved in fungal a...
Publication
Yeast Proteins may Reversibly Aggregate like Amphiphilic Molecules
Dasmeh, Pouria and Andreas Wagner. 2022. Yeast Proteins may Reversibly Aggregate like Amphiphilic Molecules. Journal of Molecular Biology, 4...
Publication
Translation stalling proline motifs are enriched in slow-growing, thermophilic, and multicellular bacteria
Brewer, Tess E. and Andreas Wagner. 2022. Translation stalling proline motifs are enriched in slow-growing, thermophilic, and multicellular ...
Publication
GroEL/S Overexpression Helps to Purge Deleterious Mutations and Reduce Genetic Diversity during Adaptive Protein Evolution
Iyengar, Bharat Ravi and Andreas Wagner. 2022. GroEL/S Overexpression Helps to Purge Deleterious Mutations and Reduce Genetic Diversity duri...
Project
Towards designing less-toxic antibiotics
Mitochondria are essential organelles found in every human cell, required to convert food into usable energy.
Publication
The Role of microRNAs in the Resistance to Colorectal Cancer Treatments
Amirkhah, Raheleh, Ali Farazmand, Muhammad Irfan-Maqsood, Olaf Wolkenhauer, and Ulf Schmitz. 2015. The Role of microRNAs in the Resistance t...
Publication
Code Biology
Barbieri, Marcello. 2015. Code Biology. Dordrecht: Springer International Publishing. doi:10.1007/978-3-319-14535-8.
Publication
The RNA World in the 21st Century—a Systems Approach to Finding Non-Coding Keys to Clinical Questions
Schmitz, Ulf, Hojjat Naderi-Meshkin, Shailendra K Gupta, Olaf Wolkenhauer, and Julio Vera. 2016. The RNA World in the 21st Century—a Systems...
Publication
Dynamics of the Mammalian Cell Cycle in Physiological and Pathological Conditions
Gérard, Claude and Albert Goldbeter. 2016. Dynamics of the Mammalian Cell Cycle in Physiological and Pathological Conditions. Wiley Interdis...
Project
Revised edition of the book ‘Biochemical Oscillations and Cellular Rhythms’
A second edition of the book (entitled Biochemical Oscillations and Cellular Rhythms.